Member Academic Sites: A Network Built for Access

NEALS is powered by its member sites – academic institutions across the world that bring research to life, lead clinical trials, and innovate in ALS care every day.

Together, these sites form the engine of ALS clinical research – NEALS members have led pivotal trials, developed biomarkers, expanded trial access, and trained the next generation of ALS researchers. From major research universities to community-based centers, NEALS members bring deep expertise, local relationships, and a shared commitment to advancing trials that matter.

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Click here for information on NEALS training programs and how your site can join our network.

A National Network of Excellence

NEALS includes more than 160 academic research sites across North America and beyond, with several international collaborators in Turkey, Japan, Australia, Italy, Israel, and India. Though diverse in size and scope, all sites share a dedication to collaboration, data quality, and patient-centered research. Newer member sites receive mentorship and support from experienced leaders to ensure equitable access and high-quality trial implementation.

Advancing Science and Treatment Innovation

NEALS member sites have collectively led and contributed to hundreds of ALS clinical trials, paving the way for new therapies and care models. Their involvement spans pivotal studies including trials for tofersen, edaravone, AMX0035, Healey ALS MyMatch, and the HEALEY ALS Platform Trial – an innovative adaptive platform trial design that is reshaping how ALS treatments are evaluated. Many serve as lead or coordinating sites in multi-center studies and publish findings in peer-reviewed journals, advancing trial design and methodology. These sites have also played key roles in launching expanded access programs, expanding investigational treatment opportunities for people living with ALS.

Innovating in Care and Community Engagement

Embedded within local ALS care systems, many NEALS sites uniquely blend research with compassionate, multidisciplinary care. They support patient education, navigation, and communication regarding trial opportunities, while local leadership fosters inclusion of underrepresented populations through targeted regional outreach.

Click here to find a NEALS site near you.

Member Sites Powering Innovation in ALS Trials

NEALS academic sites are at the forefront of innovative research models that aim to accelerate discovery and improve trial access.

< >Platform Trials
With NEALS-led training and infrastructure, sites helped launch the HEALEY ALS Platform Trial, the first-ever platform trial for ALS. Their early adoption of adaptive protocols enabled faster trial launches and shared learning across therapeutic regimens.Clinical Trial Matching
Through Healey ALS MyMatch, member sites assist with screening and enrollment into a centralized registry that helps match people living with ALS to eligible clinical trials — both within and outside the Platform Trial.Data and Biosample Sharing (ALL ALS)
Participating NEALS sites contribute critical biospecimens, digital health measures, clinical data, and patient-reported outcomes to the ALL ALS Consortium, a collaborative initiative building a robust dataset to support biomarker discovery and a deeper understanding of ALS subtypes.HEALEY ALS Platform Trial | Healey ALS MyMatch | Access for ALL in ALS